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The BENTLEY score is a risk prediction model for TTP
that was derived from a retrospective
analysis of 110 patients that included 11 patients with severe ADAMTS13 deficiency. Five parameters - see below - were found to be predictive of severe ADAMTS13 deficiency.
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NOTE: Whilst we have done our utmost to ensure the accuracy of the data in this section, users should access the original publications.
This will also allow you to see how the algorithm was created, the population studied and any limitations to the study.
All information contained in this section of Practical-Haemostasis.com is provided for educational purposes only. This information should not be used for the diagnosis or treatment of any health problem or disease.
The user of Practical-Haemostasis.com, assumes sole responsibility for any decisions made or actions taken based on the information contained herein.
1. This scoring system has a number of limitations - see References for additional information.
1. Bentley MJ, Lehman CM, et al. The utility of patient characteristics in predicting severe ADAMTS13 deficiency and response to plasma exchange. Transfusion. 2010; 50: 1654-64.
2. Bentley MJ, Wilson AR, et al. Performance of a clinical prediction score for thrombotic thrombocytopenic purpura in an independent cohort. Vox sanguinis. 2013; 105: 313-8.
3.
Bendapudi PK, Upadhyay V, et al. Clinical Scoring Systems in Thrombotic Microangiopathies. Semin Thromb Hemost. 2017; 43: 540-8.
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Updated:
27-Sep-2022