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A Practical Guide to Haemostasis


The BENTLEY Score

Introduction:

The BENTLEY score is a risk prediction model for TTP that was derived from a retrospective analysis of 110 patients that included 11 patients with severe ADAMTS13 deficiency.  Five parameters - see below - were found to be predictive of severe ADAMTS13 deficiency.


The BENTLEY Score:



Select Criteria:

Creatinine >2.0 mg/dL
-11.5 points
Platelet Count >35 x 109/L
-30 points
D-dimer >4.0 µg/mL
-10 points
Reticulocyte Count >3%
21 points
Unconjugated [Indirect] Bilirubin >1.5 mg/dL
20.5 points



Score

[Max Score 41.5]

Interpretation
 <10 points 0% risk of TTP
 20-30 points 40% risk of TTP
 >30 points 100% risk of TTP


Click HERE to Reset the algorithm


Comments:


The BENTLEY scoring system has a number of limitations - see References for additional information.