Introduction
Molecular studies in Haemostasis are and will continue, to transform our approach to the investigation and management of individuals and their families with a wide variety of disorders of Haemostasis. This section of Practical-Haemostasis.com is designed to introduce you to molecular genetics as it relates to the inherited bleeding disorders. It is not a primer on genetics - there are some excellent sites on the internet that will do that. The internet also contains a number of mutational databases related to the inherited bleeding disorders and links to these are included.
This part of the site is divided into 3 principal sections:
- Pedigree and Bayesian Risk Analysis
- Linkage Analysis
- Mutational Analysis
A further section addresses the Factor V Leiden and the Prothrombin G20210A mutations.