A Practical Guide to Haemostasis

French Mortality in TTP Score [MITS]


The French Mortality in TTP Score [MITS] is a clinical prognostic algorithm for estimating mortality in hospitalised patients with TTP.

The MITS Score:

Select Criteria:

Platelet Transfusions
1 Point
Ischaemic Stroke
1 Point
Renal Failure [Acute/Chronic Renal Failure/Need for Haemodialysis
1 Point
Myocardial Infarction
1 Point
Age ≥60 Years
2 Points
CNS Bleed
3 Points
Arterial Thrombosis
3 Points


[Max Score 12 points]

Interpretation:  In-hospital Mortality
0 0.72%
1 5.47%
2 8.33%
3 19.60%
4 26.67%
5 35.36%
6 60.00%
7-12 Too few patients to allow calculation of mortality

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The MITS scoring system is based on a national database and was used to develop the MITS prognostic risk stratified score aimed at identifying hospitalised TTP patients at the highest probability of a fatal outcome and therefore who would potentially benefit from additional/more intensive treatments.