Introduction
The PBQ was developed to screen children for von Willebrands Disease.
In children with a PBQ score of 3 and predicted to have VWD, the sensitivity was 97.2% with a specificity of 97.1%. The positive predictive value was 48.6%, and the negative predictive value was 99.9%.
The variables evaluated in the PBQ are summarised below. Each variable apart from CNS bleeds are scored from 0-4 but in addition three variables [Dental extractions, Surgery and Post-partum] may receive a score of -1 if an individual has undergone these procedures/events with no bleeding problems. A score of 4 represents the most severe symptoms.
| Epistaxis |
| Cutaneous Bruising |
| Bleeding from minor wounds |
| Oral Cavity Bleeding |
| GI Bleeding |
| Dental Extractions |
| Surgery |
| Menorrhagia |
| Post-partum Haemorrhage |
| Muscle Haematoma |
| Haemarthrosis |
| CNS Bleeding |
| Other Bleeding Problems |
| Following circumcision Umbilical stump bleeding Cephalohaematoma Macroscopic haematuria Post-venepuncture Conjunctival haemorrhage |
| Interpretation: |
|
| Normal Range | 0 - 2 for both male and female children |