Practical-Haemostasis.com - A Practical Guide and Laboratory Resource for Haemostasis

Practical-Haemostasis.com
A Practical Guide to Haemostasis

Practical-Haemostasis.com

Welcome to Practical-Haemostasis.com. This site is designed to teach Haemostasis and was written for laboratory staff, doctors in training and anyone who has an interest in Haemostasis & Thrombosis. It stems from a series of seminars that have run in Cambridge for some years and covers many of the commonly used and less commonly used laboratory tests and their interpretation.

Embolus - the App: If you would like to explore and test your knowledge of Haemostasis and Thrombosis or are working towards post-graduate exams in Haematology, please see our App [Embolus] available through the Apple store and the Google Play Store.

Dr David J Perry
Cambridge. UK

Navigation

Screening Tests

Introduction & Bleeding Questionnaires
Prothrombin Time [PT]
Activated Partial Thromboplastin Time [APTT]
Thrombin Time [TT]
Fibrinogen Assays
Summary

Factor & Inhibitor Assays

Factor Assays
Introduction
1-Stage PT-based Factor Assays
1-Stage APTT-based Factor Assays
1-Stage RVV-based Factor X Assay
2-Stage Factor VIII Assay
Chromogenic FVIII and FIX Assays
Factor XIII Assays
Monitoring Concentrates and non-factor Therapies
Inhibitor Assays
Introduction
Inhibitor Screening Tests
Bethesda Assay
Nijmegen modification
VWF Inhibitor Assays
Von Willebrand Factor [VWF] Assays
Introduction
Immunological Assays
FVIII Binding Assay
VWF Collagen Binding Assay
VWF Ristocetin Cofactor Assay
VWF Epitope-Specific Assays
RIPA Assay
VWF Multimer Analysis
VWF Propeptide [VWFpp] Assay
VWF Inhibitor Assays

Platelet Function Testing

Introduction
Light Transmission Aggregometry [LTA]
Impedance Platelet Aggregometry
PFA-100/200
VerifyNow Assay
Global Thrombosis Test
Platelet Nucleotide Assays
Flow Cytometry
Platelet Procoagulant Assays

Thrombophilia Testing

Thrombophilia Testing - Introduction
Antithrombin Assays
Protein C Assays
Protein S Assays
APCr Assays
Protein C Global Assay
Homocysteine
Antiphospholipid Assays
Introduction
Dilute Russell Viper Venom Time [dRVVT]
Kaolin Clotting Time [KCT]
Silica Clotting Time [SCT]
Taipan Venom Time
Taipan:Ecarin Ratio
Textarin:Ecarin Ratio
Dilute Thromboplastin Inhibition Test [DTI]
Anticardiolipin & Anti-β₂ GPI Assays

Fibrinolytic Assays

Introduction
D-Dimer Assays
FDP Assays
Euglobulin Clot Lysis Time [ECLT]
Alpha2-PI Assays
Plasminogen Assays
PAI-1 Assays
t-PA Assays
TAFI Assays
u-PA Assays
Venous Occlusion Test
Global Assays of Fibrinolysis
GFC Assay
CloFAL Assay
OHP Assay
CIP Assay

Genetic Tests

Introduction
Bayesian Risk Analysis
Pascal's Triangle
Linkage Analysis
Mutational Analysis
Hardy Weinberg Principle
Prothrombin F2 G20201A Mutation
Factor V Leiden Mutation

Miscellaneous Tests

Activated Clotting Time [ACT]
Anti-Xa Assays
ADAMTS13 Assays
HIT and HIT Assays
Ecarin Clotting Time [ECT]
Protamine Sulphate Neutralisation Test
Prothrombinase-induced Clotting Test
Reptilase Time
Stypven Time
ISI and INR
Bleeding Time [BT]
Heparin Cofactor II [HCII] Assays
Prothrombin F1+2 Assays

Global Tests of Haemostasis

Introduction to Global Assays
ETP Assays
TEG and ROTEM Analyses
Global Thrombosis Test
ReoRox G2 Assay
Global Assays of Fibrinolysis
GFC Assay
CloFAL Assay
OHP Assay
CIP Assay

Quality Assurance

An introduction to Quality Assurance in Haemostasis
Pre-Analytical Variables

Risk Assessment Algorithms

Risk Assessment Algorithms: Introduction
Atrial Fibrillation and Ischaemic Stroke
Atrial Fibrillation and the Risk of Bleeding
Anti-Phospholipid Syndrome [APS]
Bleeding Assessment
DIC Assessment
Heparin-induced Thrombocytopaenia [HIT]
Post-Thrombotic Syndrome
Thrombotic Microangiopathies [TMAs]
Upper Extremity Thromboses
VTED Risk In Hospitalised Patients
VTED - Diagnosis
VTED - Assessing Bleeding Risk
VTED - Risk of Recurrence
VTED and Cancer

Useful Information

Paediatric Reference Ranges
Haemostatic Drugs
DOACs and Laboratory Tests
Snake Venoms in Haemostasis
Vitamin K & Haemostasis

Home Page

Data Interpretation App

EMBOLUS - THE APP

Miscellaneous

CONTACT US
SITE MAP
PRIVACY POLICY

Comments

How to find your way around: The Site Map will show you what tests are currently available and is a quick way to move around the site. Some older, rarely performed tests may not have a unique page allocated to them but they will still be covered in the site.

Home Page: On each page you will find a link marked 'Home Page' this will take you back to this page.

Internet Browsers: The site is designed to work in Firefox, Safari, Chrome and Internet Explorer.

Copyright: Whilst you are free to use this site - we would remind you that the copyright for the site remains with the author.

Disclaimer: Whilst we have strived to create content that maps to the highest standards of professional practice, the contents of this website are for educational purposes only and should not be used to guide clinical practice. Your use of this site is at your own risk and we take no responsibility for any damage or injury arising from its use.

LINKS & References

This will contain links and references to useful papers and other relevant sites.